Medicine raw materials,Pharmaceuticals ,Advanced chemicla ,Assay-kits,Proteins,APIs
Monday, October 29, 2012
Cobalt oxalate system of law
Cobalt oxalate ancestry of anemic blush powder, chemicals. Heating hydrolysis in potassium hydroxide or sodium carbonate solution. Acrid in ammonia, hardly acrid in acid, about baffling in baptize and the oxalic acerbic solution. Irritation. Mainly acclimated as a raw actual fabricated ??of azure oxide and brownish azure and added azure amoebic compound, a azure catalyst, the indicator can aswell be acclimated as the system.
System of law:
Ammonium oxalate band-aid was added in the band-aid of azure sulfate or azure chloride, to accomplish azure oxalate Shen ingot, and again by filtration, washing, drying.
2, azure carbonate raw actual was attenuated with hydrochloric acerbic or sulfuric acid, again add the ammonium oxalate solution, to accomplish azure oxalate Shen ingot, and again by filtration, washing, drying
Packaging: The alien bag lined with artificial closed bag, net weight 25 kg. Every 40 per bag GW 25.2 kg. Export on a tray, anniversary tray net weight of 1000 kg. Anniversary tray additional burden aggregate of about 1.3 cubic meters.
Storage: Store in a dry place, not heat, moisture.
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From: Cobalt Oxide
Tuesday, October 23, 2012
Nickel sulfate chemical properties
Nickel sulfate absolute 6 molecules of baptize of condensate ofα - dejected and blooming aboveboard crystal, in 53 ℃intoβ - blazon blooming cellophane crystal. Stable at allowance temperature 40 ℃, become dejected blurred crystal. Absolute 7 baptize of condensate for the emerald blooming cellophane crystal. Have a candied taste. Hardly weathering. At about 100℃ loses 5 molecules of baptize of condensate as a baptize content, at 280 ℃becomes chicken blooming anhydrous. The average baleful dosage ( rats, peritoneal cavity) 500mg/kg. Have the baleful abeyant of. [3] [2] nickel sulfate anhydrous, six water, seven baptize 3, six baptize main. Anhydrous is chicken blooming crystals, the about physique of 3.68. Acrid in water, baffling in ethanol, ethyl ether. From 31.5 to 53.3 ℃for the condensate of six nickel sulfate six water, baptize is dejected or blooming aerial apparent body, the about physique of 2.07. Baptize acrid acidic, aqueous solution. Acrid in concentrated ammonia ( ammonium nickel ion accumulation ), but basal solubility in amoebic solvents ( Kraft 's failings, the filigree activity is too large. ). In 280℃to lose all the baptize of crystallization, 840 ℃begins to breach down, absolution three sulphur dioxide, into nickel oxide. Below 31.5 ℃for the condensate of seven nickel sulfate seven water, baptize for blooming cellophane crystals, candied and hardly astringent, calmly weathered, the about physique of 1.948. The temperature of 98~ 100 ℃. 103 ℃ loses 6 clear water. Acrid in baptize and ethanol, acutely simple to deliquescence. Nickel sulfate acknowledgment to dust crumb and amoebic matter, can sometimes could cause a blaze or explosion. Toxic, best acceptable absorption of 0.5mg/m3 in air.
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From: Cobalt Chloride
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From: Cobalt Chloride
Sunday, October 21, 2012
What is cadmium telluride target?
Cadmium telluride target attenuate blur solar beef on an automated calibration the costs abundantly above to the technology of solar beef of apparent silicon and added materials, the assembly amount of alone $ 0.87 / W. Secondly, it is the spectrum of the sun is the a lot of consistent, can blot added than 95% of the sun. The action is almost simple, accepted technology, low activity consumption, pollution-free, afterwards the end of the activity cycle, recyclable, and the backbone of the ablaze can accomplish electricity, the college the temperature, the bigger the performance. Currently the class about-face ability of 16.5%, 10.7% of the about-face ability of industrialization. The abstract ability of 28%. The development of space.
Solar brand abstention cadmium telluride targer is the closed apathetic gas at a top temperature, top abstention tellurium and cadmium, acquired by the acknowledgment in the abbreviation gas and a exhaustion environment. The acknowledgment barge is a quartz tube, in the acknowledgment process, by recycling the charwoman aqueous tellurium and cadmium recovered application a cadmium telluride solar cell, and can accomplish aught emissions.
U.S. National Class did telluride cadmium temperature agitation test, the temperature of 760-1100 degrees balloon begin that anniversary 1 actor application if the blaze bankrupt out, the absolution of the absolute cadmium absolute is 0.01 grams. Current decidedly college than the thermal ability bulb emissions of cadmium telluride-cadmium batteries.
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From: Mineral Salts
Solar brand abstention cadmium telluride targer is the closed apathetic gas at a top temperature, top abstention tellurium and cadmium, acquired by the acknowledgment in the abbreviation gas and a exhaustion environment. The acknowledgment barge is a quartz tube, in the acknowledgment process, by recycling the charwoman aqueous tellurium and cadmium recovered application a cadmium telluride solar cell, and can accomplish aught emissions.
U.S. National Class did telluride cadmium temperature agitation test, the temperature of 760-1100 degrees balloon begin that anniversary 1 actor application if the blaze bankrupt out, the absolution of the absolute cadmium absolute is 0.01 grams. Current decidedly college than the thermal ability bulb emissions of cadmium telluride-cadmium batteries.
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From: Mineral Salts
Thursday, October 18, 2012
The nature of high purity tellurium
High purity tellurium, tellurium abstention 99.999%. 5N, 6N, and 7N three specifications. An fair apparent brownish luster. Hexagonal lattice, body 6.24g/cm3. Melting point 450 ℃, the baking point of 989 ° C. Is a actinic aspect that has the attribute Te and diminutive amount 52. Brittle, agilely toxic, silver-white, non-metallic looks agnate to tin, tellurium, the actinic selenium and sulfur. Room temperature does not plan with oxygen, heating with hydrogen role in breeding hydrogen telluride, the a lot of cogent is the attributes of the use it fabricated of binary, ternary and quaternary alloys accept acceptable photoelectric achievement and thermoelectric about-face achievement . As raw materials, with a abstention of 95% to 99% of automated tellurium application the band-aid electrolysis or area melting adjustment of accumulation the arrangement acrid (or acidic). For a solar battery, a ablaze abounding diode, the radiation detector manufacturing. Is a semiconductor dopant.
It is primarily acclimated for alertness of a thermoelectric about-face element, a cooling element, a piezoelectric clear and bittersweet detectors.
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From: Mineral Salts
It is primarily acclimated for alertness of a thermoelectric about-face element, a cooling element, a piezoelectric clear and bittersweet detectors.
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From: Mineral Salts
Wednesday, October 17, 2012
The nature of the cadmium
Cadmium is a silver-white agleam metal, melting point 320.9 ℃, baking point of 765 ° C and a body of 8650 kg / m; Toughness and ductility. Cadmium apathetic blaze in boiling air and accident of brownish luster, if acrimonious oxide band formed on the apparent of the brown. High temperatures, the acute acknowledgment of cadmium and halogen, accumulation of halogenated cadmium. And sulfur compound, to accomplish CdS. Cadmium can be attenuated in acid, but does not deliquesce the alkali. Cadmium in blaze accompaniment +1. +2. The solubility of cadmium oxide and cadmium hydroxide are actual small, they are acrid in acid, but baffling in alkali. Cadmium can anatomy a array of circuitous ions, such as Cd (NH3), Cd (CN), CdCl. Larger cadmium toxicity, the the cadmium attenuated air and aliment is actively adverse to animal health, there accept been bitterly ache due to cadmium poisoning. There are several means metal cadmium from cadmium of charcoal or cadmium charcoal (such as atramentous or charcoal restore or sulfuric acerbic leaching and zinc replacement). Further ablution the the accessible electrolytic adorning and exhaustion distillation.
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From: Mineral Salts
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From: Mineral Salts
Friday, October 12, 2012
The New Information about YK-4-279
ES-FLI1 is an oncogenic fusion protein found in Ewing’s sarcoma, a crime syndicate of undifferentiated tumors that occur throughout the body.
The binding of RNA helicase A (RHA) to ES-FLI1 promotes its oncogenic function. The binding of RNA helicase A (RHA) to ES-FLI1 promotes its oncogenic function. YK-4-279 is an inhibitor of protein-protein interactions between ES-FLI1 and RHA. At 10 µM, YK-4-279 blocks RHA binding to ES-FLI1 and induces apoptosis of a panel of Ewing’s sarcoma tumor cell lines with IC50 values ranging from 0.5-2 µM.
YK-4-279 is an inhibitor of protein-protein interactions between ES-FLI1 and RHA. At 10 µM, YK-4-279 blocks RHA binding to ES-FLI1 and hastens apoptosis of a panel of Ewing’s sarcoma tumor cell lines with IC50 values ranging from 0.5 to 2 µM.1 At 1.5 mg per dose, YK-4-279 reduces the increase of Ewing’s sarcoma orthotopic xenografts in mice after treatment with the inhibitor for two weeks.
YK-4-279 also decreased ERG and ETV1 downstream target mRNA and protein expression in ETV1-fusion positive LNCaP and ERG fusion positive VCaP cells. YK-4-279 reduced the motility of LNCaP cells in a scratch assay and the invasive phenotype of both LNCaP and VCaP cells in a HUVEC invasion assay. Fusion-negative PC3 cells were unresponsive to YK-4-279. SiRNA mediated ERG knockdown in VCaP cells resulted in a loss of drug responsiveness.
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WST-8 Cell Proliferation Determination Assay Kit for Alterations Fashionable Cell
Defining the mechanisms responsible for alterations fashionable cell cycle per second patterned advance equals determinative to inferring many person diseases, near notably Crab. The detection sensitivity is higher than that for other tetrazolium salts. Cellphone proliferation essays cause equalled widely applied to measure jail cell round regulatory constituents such every bit increment components, cytokines, mitogens, and drugs.
WST-8 is more stable and less cytotoxic than the other tetrazolium salts, getting in especially utilitarian for more farsighted incubation flows. The detection sensitivity is more gamey than that for extra tetrazolium salts.
Reduction of WST-8 produces a water-soluble formazan which dissolves directly into the culture medium, eliminating the need for an additional solubilization step.
WST-8 is more stable and less cytotoxic than the other tetrazolium salts, making it especially useful for longer incubation periods. WST-8 is more stable and less cytotoxic than the other tetrazolium salts, making it especially useful for longer incubation periods. The detection sensitivity is higher than that for other tetrazolium salts.
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Thursday, October 11, 2012
The Application of Nav1.7 Sodium Channel Monoclonal Antibody (Clone S68-6)
Nav1.7 is a voltage-gated sodium channel that plays a critical persona fashionable the genesis and conduction of carry through potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the personnel casualty of part of a certain sodium communication channel may get imports. The person SCN9A gene encodes the pore-forming subunit of Nav1.7, a voltage-gated sodium communication channel. Mutations incoming SCN9A channelizes experience been related to several inherited diseases including erythromelalgia (vasodilation with burning pain), paroxysmal extreme pain disorder, and congenital indifference to pain). Nav1.7, upregulated in prostatic Cancer the Crab and ignition, equals a malignant neoplastic disease biomarker and a therapeutic target in treatment of pain.
There are voltage-gated ion channels, ligand-gated, other gating systems, and finally those that are classified differently, having more exotic characteristics. The first are voltage-gated ion channels which open and close in response to membrane potency. These are and then seperated into atomic number 11, calcium, potassium, proton, impermanent receptor, and closed-ring nucleotide-gated conducts, each of which is responsible for a unique role.
They are demo incoming the membranes that surround all biological cells and their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct grounded on duty a ionic species, such that equally sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical effects. In that respect expanse few primary compartmentalisations of gated ion channels.
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