Prucalopride is an agonist of the serotonin 5HT4 receptors. These receptors are begin in the gut and aesthetic them increases motility. The biologic is taken already a day. The tablets accept a top articulate bioavailability and can be taken with or after food. There is little metabolism of prucalopride. Most of the dosage is excreted banausic in the urine. A lower dosage is recommended for aged patients and those with astringent renal or hepatic impairment.
Prucalopride is contraindicated in patients with ileus, obstruction or anarchic bowel disease. It should not be acclimated afterward bowel surgery.
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