Prostaglandin E synthase (PGES) catalyzes the isomerization of PGH2 to PGE2. Cytosolic and microsomal PGES enzymes accept been cloned and characterized. Cytosolic PGES (cPGES) is a glutathione-dependent agitator with a predicted admeasurement of 18.6 kDa. The agitator is bidding in a array of tissues and cells, the levels of which are artless by analysis with interleukin-1β and TNF-α. However, agitator announcement increases about 3-fold in rat academician afterward lipopolysaccharide treatment.
Application of Prostaglandin E Synthase (cytosolic) Western Ready Control
positive control for WB · Source: human recombinant protein expressed in E.coli · Mr: 18 kDa · Prostaglandin E synthase (PGES) catalyzes the isomerization of PGH2 to PGE2. Cytosolic and microsomal PGES enzymes have been cloned and characterized. Cytosolic PGES (cPGES) is a glutathione-dependent enzyme with a predicted size of 18.6 kDa. The enzyme is expressed in a variety of tissues and cells, the levels of which are unaffected by treatment with interleukin-1β and TNF-α.1 However, enzyme expression increases approximately 3-fold in rat brain following lipopolysaccharide treatment.
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