Specifications of 2-Amino-6-bromopyridine

2-Amino-6-bromopyridine
CAS Number: 19798-81-3
Molecular Weight: 173.01
Molecular Formula: C5H5BrN2
Physical Appearance: White to tan powder
2-Amino-6-bromopyridine, employed in an efficient one-pot synthesis of 7-azaindoles. Used in the synthesis of anti-HIV agents.
When 2-aminopyridine and bromine in the anatomy of vapour adulterated with nitrogen are anesthetized over brush at 500°, a agitated acknowledgment takes place, abundant carbon is deposited and a circuitous admixture of brominated aminopyridines is formed.
isomeric monobromo-compounds could be abandoned from the mixture, i.e. 2-amino-3-bromopyridine, 2-amino-5-bromopyridine and 2-amino-6-bromopyridine. It independent added 3 dibromo-compounds (2-amino-3,5-dibromopyridine, 2-amino-3,6-dibromo-pyridine and 2-amino-5,6-dibromopyridine) and one tribromo-compound (2-amino-3,5,6-tribromopyridine).
The acknowledgment declared differs appreciably from the bromination of 2-amino-pyridine at allowance temperature, by the endure action a admixture of alone 2-amino-5-bromo-pyridine and 2-amino-3,5-dibromopyridine getting formed.
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