Steatosis Colorimetric Assay Kit, also known as adipose more alive, is a pathological process qualified by antidromic accruement of lipide inside cells. Although childlike steatosis may not be associated with significant impairment of liver function, excessive fat accumulation can lead to cirrhosis and even liver failure.
Cayman Chemical’s Steatosis Colorimetric check Kit caters a accessible puppet since evaluating steatosis risk of drug candidates. In this assay, Oil Red O is used to stain neutral lipids in hepatocytes. Lipid accumulation costs then quantified exploitation a crustal plate lecturer afterwards the dye is extracted from the lipid droplets. Chloroquine equals included inward the kit up because a convinced control.The molecular mechanisms involved in non-alcoholic steatosis are poorly understood and little information is accessible on duty the pathway(atomic number 16) responsible for for progressive hepatocellular hurt being lipid aggregation.
Detecting hepatotoxicity personifies an necessary factor of the drug discovery process and includes steatosis as one of the key parameters evaluated. Steatosis Colorimetric Assay Kit provides a method for evaluating steatosis risk of drug candidates using Oil Red O to stain neutral lipids fashionable hepatocytes.
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